{"id":94872,"date":"2022-04-06T14:54:41","date_gmt":"2022-04-06T11:54:41","guid":{"rendered":"https:\/\/sanatate.md\/?p=94872"},"modified":"2022-04-08T11:35:50","modified_gmt":"2022-04-08T08:35:50","slug":"avem-in-sfarsit-un-genom-uman-complet","status":"publish","type":"post","link":"https:\/\/sanatate.md\/ro\/avem-in-sfarsit-un-genom-uman-complet\/","title":{"rendered":"Avem \u00een sf\u00e2r\u0219it un genom uman complet"},"content":{"rendered":"

Aproximativ 8% din genom lipsea din versiunile anterioare ale c\u0103r\u021bii de instruc\u021biuni genetice<\/h3>\n

Cercet\u0103torii au descifrat \u00een sf\u00e2r\u0219it, genomul uman \u0219i l-au inclus \u00eentr-o carte complet\u0103 de instruc\u021biuni genetice umane, de la scoar\u021b\u0103 la scoar\u021b\u0103.<\/p>\n

Finalizarea genomului uman a fost anun\u021bat\u0103 de c\u00e2teva ori \u00een trecut, \u00eens\u0103 acestea erau de fapt ni\u0219te schi\u021be incomplete. \u201eDe aceast\u0103 dat\u0103 chiar vorbim serios\u201d, spune Evan Eichler, genetician uman \u0219i investigator al Institutului Medical Howard Hughes de la Universitatea Washington din Seattle.<\/p>\n

\"\"<\/p>\n

Genomul finalizat este prezentat \u00eentr-o serie de lucr\u0103ri publicate online, pe 31 martie \u00een Science and Nature Methods.<\/p>\n

O echip\u0103 interna\u021bional\u0103 de cercet\u0103tori, inclusiv \u0219i Eichler, au folosit o nou\u0103 tehnologie de secven\u021biere a ADN-ului pentru a descifra por\u021biuni repetitive de ADN care au fost redactate dintr-o versiune anterioar\u0103 a genomului, folosit\u0103 pe scar\u0103 larg\u0103 ca referin\u021b\u0103 pentru ghidarea cercet\u0103rilor biomedicale.<\/p>\n

Descifrarea acestor por\u021biuni adaug\u0103 aproximativ 200 de milioane de baze ADN, aproximativ 8% din genom, la manualul de instruc\u021biuni, raporteaz\u0103 cercet\u0103torii. Acesta este \u00een esen\u021b\u0103 un \u00eentreg capitol, unul suculent. El con\u021bine prima privire asupra bra\u021belor scurte ale unor cromozomi, gene necunoscute \u0219i structura unei p\u0103r\u021bi importante ale cromozomului uman \u2013 centromerul, care este parte component\u0103, responsabil\u0103 de divizarea ADN-ului.<\/p>\n

\u201eUnele dintre regiunile care lipseau din carte, se dovedesc de fapt, a fi cele mai interesante\u201d, spune Rajiv McCoy, genetician la Universitatea Johns Hopkins, care f\u0103cea parte din echipa cunoscut\u0103 sub numele de Consor\u021biul Telomere-to-Telomere (T2T), care a reunit genomul uman complet. \u201eA fost curios pentru noi s\u0103 arunc\u0103m o prim\u0103 privire \u00een aceste regiuni \u0219i\u00a0 s\u0103 vedem ce comori putem g\u0103si.\u201d<\/p>\n

Datele sunt deja disponibile pentru ca al\u021bi cercet\u0103tori s\u0103 le exploreze. Iar unii, precum geneticianul Ting Wang de la \u0218coala de Medicin\u0103 a Universit\u0103\u021bii Washington din St. Louis, au aprofundat cuno\u0219tin\u021bele c\u0103p\u0103tate. \u201eA avea o referin\u021b\u0103 complet\u0103 a genomului uman, \u00eembun\u0103t\u0103\u021be\u0219te cu siguran\u021b\u0103 toate studiile biomedicale… Este o resurs\u0103 extrem de util\u0103\u201d, spune el. \u201eNu exist\u0103 nicio \u00eendoial\u0103 c\u0103 aceasta este o realizare extrem de important\u0103.\u201d<\/p>\n

Autor<\/strong> \u2013 Siluan Steg\u0103rescu<\/a>
\nSurs\u0103<\/strong> \u2013 Science News<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Aproximativ 8% din genom lipsea din versiunile anterioare ale c\u0103r\u021bii de instruc\u021biuni genetice Cercet\u0103torii au descifrat \u00een sf\u00e2r\u0219it, genomul uman \u0219i l-au inclus \u00eentr-o carte complet\u0103 de instruc\u021biuni genetice umane, de la scoar\u021b\u0103 la scoar\u021b\u0103. Finalizarea genomului uman a fost anun\u021bat\u0103 de c\u00e2teva ori \u00een trecut, \u00eens\u0103 acestea erau de fapt ni\u0219te schi\u021be incomplete. \u201eDe […]<\/p>\n","protected":false},"author":594,"featured_media":94873,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[1293,1294],"tags":[7437],"class_list":{"0":"post-94872","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-articole","8":"category-sanatate","9":"tag-enom-uman-complet"},"yoast_head":"\nAvem \u00een sf\u00e2r\u0219it un genom uman complet<\/title>\n<meta name=\"description\" content=\"Cercet\u0103torii au descifrat \u00een sf\u00e2r\u0219it, genomul uman \u0219i l-au inclus \u00eentr-o carte complet\u0103 de instruc\u021biuni genetice umane, de la scoar\u021b\u0103 la scoart\u0103. Finalizarea genomului uman a fost anun\u021bat\u0103 de c\u00e2teva ori \u00een trecut, dar acestea erau de fapt schi\u021be incomplete. \u201eDe data asta chiar vorbim serios\u201d, spune Evan Eichler, genetician uman \u0219i investigator al Institutului Medical Howard Hughes de la Universitatea Washington din Seattle.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sanatate.md\/ro\/avem-in-sfarsit-un-genom-uman-complet\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Avem \u00een sf\u00e2r\u0219it un genom uman complet\" \/>\n<meta property=\"og:description\" content=\"Cercet\u0103torii au descifrat \u00een sf\u00e2r\u0219it, genomul uman \u0219i l-au inclus \u00eentr-o carte complet\u0103 de instruc\u021biuni genetice umane, de la scoar\u021b\u0103 la scoart\u0103. 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