{"id":95504,"date":"2022-04-21T16:00:20","date_gmt":"2022-04-21T13:00:20","guid":{"rendered":"https:\/\/sanatate.md\/?p=95504"},"modified":"2022-04-21T16:00:43","modified_gmt":"2022-04-21T13:00:43","slug":"poate-depresia-sa-provoace-modificari","status":"publish","type":"post","link":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/","title":{"rendered":"Poate depresia s\u0103 provoace modific\u0103ri de durat\u0103 ale celulelor sistemului imun?"},"content":{"rendered":"

Pentru prima dat\u0103 \u00een istorie, un nou studiu a stabilit o leg\u0103tur\u0103 \u00eentre tulbur\u0103rile depresive persistente pe termen lung \u0219i modific\u0103rile mecanice ale celulelor sanguine \u0219i modific\u0103rile formei \u0219i func\u021biei celulelor imune.<\/h3>\n

Studiul, publicat \u00een jurnalul Translational Psychiatry, a fost realizat de cercet\u0103tori de la Universitatea din Zurich din Elve\u021bia, Technische Universit\u00e4t Dresden (TU Dresden), Max Planck Institutes for Science of Light \u0219i Max-Planck-Zentrum f\u00fcr Physik und Medizin Erlangen \u00een Germania.<\/p>\n

\"\"<\/p>\n

Cercet\u0103torii au efectuat un studiu transversal de tip caz-control folosind un test care ar putea determina capacitatea unei celule de a-\u0219i schimba forma folosind mostre de s\u00e2nge s\u0103n\u0103toase pe baza modific\u0103rilor imaginilor celulelor sanguine.<\/p>\n

Focalizare dubl\u0103: terapii biologice \u0219i psihologice<\/h3>\n

Autorul principal al studiului Andreas Walther, consider\u0103 c\u0103 este esen\u021bial s\u0103 avanseze terapiile biologice \u0219i psihologice pentru a trata st\u0103rile depresive mai eficient \u0219i mai sustenabil pe termen lung. El explic\u0103:<\/p>\n

\u201eLucr\u0103m \u00een paralel la cercetarea terapiilor farmacologice pentru a \u00eembun\u0103t\u0103\u021bi disfunc\u021biile biologice, precum \u0219i la terapiile psihologice pentru a \u00eembun\u0103t\u0103\u021bi procesele cognitive \u0219i emo\u021bionale disfunc\u021bionale. \u00centr-adev\u0103r, \u00een opinia mea, doar o abordare holistic\u0103 poate \u00een\u021belege \u0219i trata eficient aceast\u0103 tulburare complex\u0103 \u0219i, sper\u0103m, s\u0103 previn\u0103 mult\u0103 suferin\u021b\u0103 \u00een viitor.\u201d<\/p>\n

Cum a fost realizat studiul<\/h3>\n

Studiul a inclus 69 de persoane pre evaluate cu risc crescut de tulbur\u0103ri depresive \u0219i 70 de pacien\u021bi din lotul control, s\u0103n\u0103toase. Participan\u021bii au fost supu\u0219i unei evalu\u0103ri clinice folosind un proces de interviu clinic recunoscut la nivel global pentru diagnosticarea afec\u021biunilor de s\u0103n\u0103tate mintal\u0103, numit Interviul de Diagnostic Interna\u021bional Compozit.<\/p>\n

Inteligen\u021ba artificial\u0103, special destinat\u0103, a scanat peste 16 milioane de imagini cu celule sanguine. Aceste imagini au fost apoi clasificate \u00een principalele tipuri de celule sanguine \u0219i m\u0103surate folosind parametri precum dimensiunea celulei, \u00een plus fa\u021b\u0103 de capacitatea lor de a-\u0219i schimba forma \u0219i de a prezenta deformabilitatea membranei celulare.<\/p>\n

Oamenii de \u0219tiin\u021b\u0103 au descoperit c\u0103 celulele sistemului imun (monocite, limfocite \u0219i neutrofile) au fost cele mai deformate la pacien\u021bii cu tulbur\u0103ri depresive persistente pe parcursul vie\u021bii, dec\u00e2t la subiec\u021bii s\u0103n\u0103to\u0219i.<\/p>\n

Dou\u0103 subtipuri de depresie<\/h3>\n

O tulburare depresiv\u0103 major\u0103 necesit\u0103 o faz\u0103 de dou\u0103 s\u0103pt\u0103m\u00e2ni pentru a fi diagnosticat\u0103 \u0219i pentru a corespunde criteriilor necesare. Diagnosticat\u0103 \u00een mod similar, o tulburare depresiv\u0103 persistent\u0103 (PDD) dureaz\u0103 mai mult de doi ani \u0219i poate afecta o persoan\u0103 pe tot parcursul vie\u021bii. Tulbur\u0103rile depresive sunt principalele cauze de dizabilitate la nivel mondial.<\/p>\n

Depresia provoac\u0103 inflama\u021bie cronic\u0103 de un grad mai sc\u0103zut \u0219i cre\u0219te produc\u021bia de hormoni de stres. Ambele efecte pot interfera poten\u021bial cu structura celulelor imune prin deformarea formei acestora.<\/p>\n

Nu este clar dac\u0103 cre\u0219terea deformabilit\u0103\u021bii celulelor imune care apare cu PDD confer\u0103 o activitate excesiv\u0103 sau insuficient\u0103 a sistemului imunitar. Cer este c\u0103, ambele st\u0103ri sunt nocive pentru s\u0103n\u0103tate.<\/p>\n

Dr. Jean Kim, profesor asistent clinic de psihiatrie la Universitatea George Washington, despre concluziile studiului:<\/p>\n

\u201eRezultatele postuleaz\u0103 c\u0103 deformabilitatea celulelor sanguine este un marker al st\u0103rilor patologice ale celulelor imune, de\u0219i pare oarecum neclar \u0219i variabil \u00een ce direc\u021bie se orienteaz\u0103 – cu hiperactivitate imun\u0103 sau hipoactivitate\u201d, a zis ea.<\/p>\n

\u201eSe consider\u0103 c\u0103 hormonii de stres, cum ar fi glucocorticoizii, m\u0103resc nivelul leucocitelor din s\u00e2nge \u0219i indic\u0103 asupra unei inflama\u021bii atunci c\u00e2nd axa hipotalam-hipofizar-suprarenal\u0103 este activat\u0103 \u00een timpul anxiet\u0103\u021bii sau depresiei\u201d, a ad\u0103ugat ea.<\/p>\n

Efecte suplimentare asupra organismului<\/h3>\n

Dr. Sheldon Zablow, psihiatru \u0219i profesor asistent voluntar de psihiatrie infantil\u0103 la UC San Diego School of Medicine:<\/p>\n

\u201eInflama\u021bia cronic\u0103, precum \u0219i depresia cronic\u0103 induc secre\u021bia la o mare varietate de substan\u021be chimice, cum ar fi cortizolul, care deformeaz\u0103 structura celulelor albe ale imunit\u0103\u021bii\u201d, a spus dr. Zablow.<\/p>\n

\u201eAceast\u0103 deformabilitate (indus\u0103 de depresie) a leucocitelor reduce capacitatea acestora de a lupta \u00eempotriva infec\u021biilor sau de a repara daunele \u0219i cre\u0219te riscul apari\u021biei unei game largi de boli, \u00een afar\u0103 de depresie… inflama\u021bia cronic\u0103 cauzeaz\u0103 sau agraveaz\u0103 obezitatea, bolile cardio-vasculare, demen\u021ba, diabetul \u0219i maladiile autoimune.\u201d<\/p>\n

Un test de s\u00e2nge pentru depresie?<\/h3>\n

Dr. Zablow a spus c\u0103, \u00een viitor, testarea deformabilit\u0103\u021bii celulelor sanguine ar putea deveni standard pentru persoanele cu inflama\u021bie cronic\u0103 sau pentru cei cu risc crescut de depresie pe termen lung.<\/p>\n

Dr. Kim a numit descoperirile interesante, dar a spus c\u0103 sunt necesare mai multe cercet\u0103ri pentru a \u00een\u021belege implica\u021biile practice mai largi.<\/p>\n

\u201eDac\u0103 studiile ulterioare continu\u0103 s\u0103 reproduc\u0103 aceste tendin\u021be \u0219i descoperiri, ar putea chiar, \u00eentr-o zi s\u0103 contribuie la dezvoltarea unui test de s\u00e2nge pentru a \u201edetecta\u201d depresia.\u201d<\/p>\n

Autor<\/strong> \u2013 Siluan Steg\u0103rescu<\/a>
\nSurs\u0103<\/strong> \u2013 medicalnewstoday.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Pentru prima dat\u0103 \u00een istorie, un nou studiu a stabilit o leg\u0103tur\u0103 \u00eentre tulbur\u0103rile depresive persistente pe termen lung \u0219i modific\u0103rile mecanice ale celulelor sanguine \u0219i modific\u0103rile formei \u0219i func\u021biei celulelor imune. Studiul, publicat \u00een jurnalul Translational Psychiatry, a fost realizat de cercet\u0103tori de la Universitatea din Zurich din Elve\u021bia, Technische Universit\u00e4t Dresden (TU Dresden), […]<\/p>\n","protected":false},"author":594,"featured_media":95501,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[1293,1294],"tags":[7527],"class_list":{"0":"post-95504","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-articole","8":"category-sanatate","9":"tag-celulelor-sistemului-imun"},"yoast_head":"\nPoate depresia s\u0103 provoace modific\u0103ri de durat\u0103 ale celulelor sistemului imun?<\/title>\n<meta name=\"description\" content=\"Pentru prima dat\u0103 \u00een istorie, un nou studiu a stabilit o leg\u0103tur\u0103 \u00eentre tulbur\u0103rile depresive persistente pe termen lung \u0219i modific\u0103rile mecanice ale celulelor sanguine \u0219i modific\u0103rile formei \u0219i func\u021biei celulelor imune.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Poate depresia s\u0103 provoace modific\u0103ri de durat\u0103 ale celulelor sistemului imun?\" \/>\n<meta property=\"og:description\" content=\"Pentru prima dat\u0103 \u00een istorie, un nou studiu a stabilit o leg\u0103tur\u0103 \u00eentre tulbur\u0103rile depresive persistente pe termen lung \u0219i modific\u0103rile mecanice ale celulelor sanguine \u0219i modific\u0103rile formei \u0219i func\u021biei celulelor imune.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/\" \/>\n<meta property=\"og:site_name\" content=\"Sanatate.md\" \/>\n<meta property=\"article:author\" content=\"https:\/\/www.facebook.com\/MoldovaSanatate\/\" \/>\n<meta property=\"article:published_time\" content=\"2022-04-21T13:00:20+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-04-21T13:00:43+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sanatate.md\/wp-content\/uploads\/2022\/04\/sanatate1-14.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"628\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Sanatate\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Scris de\" \/>\n\t<meta name=\"twitter:data1\" content=\"Sanatate\" \/>\n\t<meta name=\"twitter:label2\" content=\"Timp estimat pentru citire\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/poate-depresia-sa-provoace-modificari\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/poate-depresia-sa-provoace-modificari\\\/\"},\"author\":{\"name\":\"Sanatate\",\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/#\\\/schema\\\/person\\\/4ffabf929ee3c3fe77c0fd4a0dfe7eb2\"},\"headline\":\"Poate depresia s\u0103 provoace modific\u0103ri de durat\u0103 ale celulelor sistemului imun?\",\"datePublished\":\"2022-04-21T13:00:20+00:00\",\"dateModified\":\"2022-04-21T13:00:43+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/poate-depresia-sa-provoace-modificari\\\/\"},\"wordCount\":820,\"publisher\":{\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/poate-depresia-sa-provoace-modificari\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/sanatate.md\\\/wp-content\\\/uploads\\\/2022\\\/04\\\/sanatate1-14.jpg\",\"keywords\":[\"celulelor sistemului imun\"],\"articleSection\":[\"Articole\",\"S\u0103n\u0103tate\"],\"inLanguage\":\"ro-RO\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/poate-depresia-sa-provoace-modificari\\\/\",\"url\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/poate-depresia-sa-provoace-modificari\\\/\",\"name\":\"Poate depresia s\u0103 provoace modific\u0103ri de durat\u0103 ale celulelor sistemului imun?\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/poate-depresia-sa-provoace-modificari\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/poate-depresia-sa-provoace-modificari\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/sanatate.md\\\/wp-content\\\/uploads\\\/2022\\\/04\\\/sanatate1-14.jpg\",\"datePublished\":\"2022-04-21T13:00:20+00:00\",\"dateModified\":\"2022-04-21T13:00:43+00:00\",\"description\":\"Pentru prima dat\u0103 \u00een istorie, un nou studiu a stabilit o leg\u0103tur\u0103 \u00eentre tulbur\u0103rile depresive persistente pe termen lung \u0219i modific\u0103rile mecanice ale celulelor sanguine \u0219i modific\u0103rile formei \u0219i func\u021biei celulelor imune.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/poate-depresia-sa-provoace-modificari\\\/#breadcrumb\"},\"inLanguage\":\"ro-RO\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/sanatate.md\\\/ro\\\/poate-depresia-sa-provoace-modificari\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"ro-RO\",\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/poate-depresia-sa-provoace-modificari\\\/#primaryimage\",\"url\":\"https:\\\/\\\/sanatate.md\\\/wp-content\\\/uploads\\\/2022\\\/04\\\/sanatate1-14.jpg\",\"contentUrl\":\"https:\\\/\\\/sanatate.md\\\/wp-content\\\/uploads\\\/2022\\\/04\\\/sanatate1-14.jpg\",\"width\":1200,\"height\":628},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/poate-depresia-sa-provoace-modificari\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u0413\u043b\u0430\u0432\u043d\u0430\u044f \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0430\",\"item\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Poate depresia s\u0103 provoace modific\u0103ri de durat\u0103 ale celulelor sistemului imun?\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/#website\",\"url\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/\",\"name\":\"Sanatate.md\",\"description\":\"\u0416\u0443\u0440\u043d\u0430\u043b \u0434\u043b\u044f \u0432\u0441\u0435\u0439 \u0441\u0435\u043c\u044c\u0438 \u0432 \u041c\u043e\u043b\u0434\u043e\u0432\u0435\",\"publisher\":{\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ro-RO\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/#organization\",\"name\":\"SANATATE\",\"url\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ro-RO\",\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/sanatate.md\\\/wp-content\\\/uploads\\\/2022\\\/01\\\/sanatate-logo.svg\",\"contentUrl\":\"https:\\\/\\\/sanatate.md\\\/wp-content\\\/uploads\\\/2022\\\/01\\\/sanatate-logo.svg\",\"width\":\"1024\",\"height\":\"1024\",\"caption\":\"SANATATE\"},\"image\":{\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/#\\\/schema\\\/person\\\/4ffabf929ee3c3fe77c0fd4a0dfe7eb2\",\"name\":\"Sanatate\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ro-RO\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/f3830c0218d683870deca26da36bdc17b860f9e81c38e1b28dcf6976bb616bb8?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/f3830c0218d683870deca26da36bdc17b860f9e81c38e1b28dcf6976bb616bb8?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/f3830c0218d683870deca26da36bdc17b860f9e81c38e1b28dcf6976bb616bb8?s=96&d=mm&r=g\",\"caption\":\"Sanatate\"},\"description\":\"Revista Sanatate Contacte: Telefon: 068 585 053; 068 199 951 Adresa: str. V. P\u00e2rc\u0103lab, 30\\\/1, Chi\u0219in\u0103u Toate articole\",\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/MoldovaSanatate\\\/\",\"https:\\\/\\\/www.instagram.com\\\/sanatate_moldova\\\/\"],\"url\":\"https:\\\/\\\/sanatate.md\\\/ro\\\/author\\\/sanatatero\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Poate depresia s\u0103 provoace modific\u0103ri de durat\u0103 ale celulelor sistemului imun?","description":"Pentru prima dat\u0103 \u00een istorie, un nou studiu a stabilit o leg\u0103tur\u0103 \u00eentre tulbur\u0103rile depresive persistente pe termen lung \u0219i modific\u0103rile mecanice ale celulelor sanguine \u0219i modific\u0103rile formei \u0219i func\u021biei celulelor imune.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/","og_locale":"ro_RO","og_type":"article","og_title":"Poate depresia s\u0103 provoace modific\u0103ri de durat\u0103 ale celulelor sistemului imun?","og_description":"Pentru prima dat\u0103 \u00een istorie, un nou studiu a stabilit o leg\u0103tur\u0103 \u00eentre tulbur\u0103rile depresive persistente pe termen lung \u0219i modific\u0103rile mecanice ale celulelor sanguine \u0219i modific\u0103rile formei \u0219i func\u021biei celulelor imune.","og_url":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/","og_site_name":"Sanatate.md","article_author":"https:\/\/www.facebook.com\/MoldovaSanatate\/","article_published_time":"2022-04-21T13:00:20+00:00","article_modified_time":"2022-04-21T13:00:43+00:00","og_image":[{"width":1200,"height":628,"url":"https:\/\/sanatate.md\/wp-content\/uploads\/2022\/04\/sanatate1-14.jpg","type":"image\/jpeg"}],"author":"Sanatate","twitter_card":"summary_large_image","twitter_misc":{"Scris de":"Sanatate","Timp estimat pentru citire":"5 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/#article","isPartOf":{"@id":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/"},"author":{"name":"Sanatate","@id":"https:\/\/sanatate.md\/ro\/#\/schema\/person\/4ffabf929ee3c3fe77c0fd4a0dfe7eb2"},"headline":"Poate depresia s\u0103 provoace modific\u0103ri de durat\u0103 ale celulelor sistemului imun?","datePublished":"2022-04-21T13:00:20+00:00","dateModified":"2022-04-21T13:00:43+00:00","mainEntityOfPage":{"@id":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/"},"wordCount":820,"publisher":{"@id":"https:\/\/sanatate.md\/ro\/#organization"},"image":{"@id":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/#primaryimage"},"thumbnailUrl":"https:\/\/sanatate.md\/wp-content\/uploads\/2022\/04\/sanatate1-14.jpg","keywords":["celulelor sistemului imun"],"articleSection":["Articole","S\u0103n\u0103tate"],"inLanguage":"ro-RO"},{"@type":"WebPage","@id":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/","url":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/","name":"Poate depresia s\u0103 provoace modific\u0103ri de durat\u0103 ale celulelor sistemului imun?","isPartOf":{"@id":"https:\/\/sanatate.md\/ro\/#website"},"primaryImageOfPage":{"@id":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/#primaryimage"},"image":{"@id":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/#primaryimage"},"thumbnailUrl":"https:\/\/sanatate.md\/wp-content\/uploads\/2022\/04\/sanatate1-14.jpg","datePublished":"2022-04-21T13:00:20+00:00","dateModified":"2022-04-21T13:00:43+00:00","description":"Pentru prima dat\u0103 \u00een istorie, un nou studiu a stabilit o leg\u0103tur\u0103 \u00eentre tulbur\u0103rile depresive persistente pe termen lung \u0219i modific\u0103rile mecanice ale celulelor sanguine \u0219i modific\u0103rile formei \u0219i func\u021biei celulelor imune.","breadcrumb":{"@id":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/#breadcrumb"},"inLanguage":"ro-RO","potentialAction":[{"@type":"ReadAction","target":["https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/"]}]},{"@type":"ImageObject","inLanguage":"ro-RO","@id":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/#primaryimage","url":"https:\/\/sanatate.md\/wp-content\/uploads\/2022\/04\/sanatate1-14.jpg","contentUrl":"https:\/\/sanatate.md\/wp-content\/uploads\/2022\/04\/sanatate1-14.jpg","width":1200,"height":628},{"@type":"BreadcrumbList","@id":"https:\/\/sanatate.md\/ro\/poate-depresia-sa-provoace-modificari\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u0413\u043b\u0430\u0432\u043d\u0430\u044f \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0430","item":"https:\/\/sanatate.md\/ro\/"},{"@type":"ListItem","position":2,"name":"Poate depresia s\u0103 provoace modific\u0103ri de durat\u0103 ale celulelor sistemului imun?"}]},{"@type":"WebSite","@id":"https:\/\/sanatate.md\/ro\/#website","url":"https:\/\/sanatate.md\/ro\/","name":"Sanatate.md","description":"\u0416\u0443\u0440\u043d\u0430\u043b \u0434\u043b\u044f \u0432\u0441\u0435\u0439 \u0441\u0435\u043c\u044c\u0438 \u0432 \u041c\u043e\u043b\u0434\u043e\u0432\u0435","publisher":{"@id":"https:\/\/sanatate.md\/ro\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sanatate.md\/ro\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ro-RO"},{"@type":"Organization","@id":"https:\/\/sanatate.md\/ro\/#organization","name":"SANATATE","url":"https:\/\/sanatate.md\/ro\/","logo":{"@type":"ImageObject","inLanguage":"ro-RO","@id":"https:\/\/sanatate.md\/ro\/#\/schema\/logo\/image\/","url":"https:\/\/sanatate.md\/wp-content\/uploads\/2022\/01\/sanatate-logo.svg","contentUrl":"https:\/\/sanatate.md\/wp-content\/uploads\/2022\/01\/sanatate-logo.svg","width":"1024","height":"1024","caption":"SANATATE"},"image":{"@id":"https:\/\/sanatate.md\/ro\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/sanatate.md\/ro\/#\/schema\/person\/4ffabf929ee3c3fe77c0fd4a0dfe7eb2","name":"Sanatate","image":{"@type":"ImageObject","inLanguage":"ro-RO","@id":"https:\/\/secure.gravatar.com\/avatar\/f3830c0218d683870deca26da36bdc17b860f9e81c38e1b28dcf6976bb616bb8?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/f3830c0218d683870deca26da36bdc17b860f9e81c38e1b28dcf6976bb616bb8?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/f3830c0218d683870deca26da36bdc17b860f9e81c38e1b28dcf6976bb616bb8?s=96&d=mm&r=g","caption":"Sanatate"},"description":"Revista Sanatate Contacte: Telefon: 068 585 053; 068 199 951 Adresa: str. V. P\u00e2rc\u0103lab, 30\/1, Chi\u0219in\u0103u Toate articole","sameAs":["https:\/\/www.facebook.com\/MoldovaSanatate\/","https:\/\/www.instagram.com\/sanatate_moldova\/"],"url":"https:\/\/sanatate.md\/ro\/author\/sanatatero\/"}]}},"_links":{"self":[{"href":"https:\/\/sanatate.md\/ro\/wp-json\/wp\/v2\/posts\/95504","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sanatate.md\/ro\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sanatate.md\/ro\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sanatate.md\/ro\/wp-json\/wp\/v2\/users\/594"}],"replies":[{"embeddable":true,"href":"https:\/\/sanatate.md\/ro\/wp-json\/wp\/v2\/comments?post=95504"}],"version-history":[{"count":0,"href":"https:\/\/sanatate.md\/ro\/wp-json\/wp\/v2\/posts\/95504\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sanatate.md\/ro\/wp-json\/wp\/v2\/media\/95501"}],"wp:attachment":[{"href":"https:\/\/sanatate.md\/ro\/wp-json\/wp\/v2\/media?parent=95504"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sanatate.md\/ro\/wp-json\/wp\/v2\/categories?post=95504"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sanatate.md\/ro\/wp-json\/wp\/v2\/tags?post=95504"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}